Dr. Claudiu T. Supuran received his BSc in chemistry from the Polytechnic University of Bucharest, Romania (1987) and PhD in chemistry at the same university in 1991. In 1990, he became Assistant and then Associate Professor of Chemistry at the University of Bucharest. He was Visiting Scholar at the University of Florida, Gainesville, United States, at Griffith University, Brisbane, Australia, and Visiting Professor at University of La Plata, Argentina. In 1995 he moved to the University of Florence, Italy, where he is currently Full Professor in the Department of Neuroscience, Psychology, Medicine and Child Health. His main research interests include design of enzyme inhibitors and activators, heterocyclic chemistry, chemistry of sulfonamides, sulfamates, and sulfamides, biologically active organo-element derivatives, QSAR studies, X-ray crystallography of metallo-enzymes, metal complexes with biologically active ligands (metal-based drugs), carbonic anhydrases, cyclooxygenases, serine proteases, matrix metalloproteinases, bacterial proteases, and amino acid derivatives among others. He has published more than 1900 papers in these fields.
Télécharger le livre :  Tyrosinase

Tyrosinase, Volume 56 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Overview on tyrosinases (genetics, molecular biology, phylogenetic relationship), Catalytic...
Editeur : Academic Press
Parution : 2024-09-18

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120,27

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Télécharger le livre :  Bacterial Carbonic Anhydrases

Bacterial Carbonic Anhydrases, Volume 55 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Overview on bacterial CA genetic families,Bacterial a-CAs,Bacterial ß-CAs,...
Editeur : Academic Press
Parution : 2024-09-03

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120,27

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Télécharger le livre :  Purinergic Receptors and their Modulators

This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of...
Editeur : Springer
Parution : 2023-09-28
Collection : Topics in Medicinal Chemistry
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304,89

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Télécharger le livre :  Metalloenzymes

Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of...
Editeur : Academic Press
Parution : 2023-08-30

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179,35

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Télécharger le livre :  Antiprotozoal Drug Development and Delivery

This book reviews new promising drug targets for Neglected Tropical Diseases (NTDs), with a special focus on antiprotozoal drugs against trpyanosomatids Trypanosoma cruzi and Leishmania spp. The book offers a comprehensive overview of the most recent studied targets,...
Editeur : Springer
Parution : 2022-06-24
Collection : Topics in Medicinal Chemistry
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304,89

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Télécharger le livre :  pH-Interfering Agents as Chemosensitizers in Cancer Therapy

pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological...
Editeur : Academic Press
Parution : 2020-09-03

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163,52

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Télécharger le livre :  Carbonic Anhydrases

Carbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on...
Editeur : Academic Press
Parution : 2019-07-17

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232,10

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Télécharger le livre :  Zinc Enzyme Inhibitors

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and...
Editeur : Springer
Parution : 2016-11-04
Collection : Topics in Medicinal Chemistry
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231,04

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Télécharger le livre :  Carbonic Anhydrases as Biocatalysts

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. TheCarbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents...
Editeur : Elsevier
Parution : 2015-01-14

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189,90

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Télécharger le livre :  Drug Design of Zinc-Enzyme Inhibitors

Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and...
Editeur : Wiley
Parution : 2009-10-22
Collection : Wiley Series in Drug Discovery and Development
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255,26

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