Téléchargez le livre : New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids

New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids



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Éditeur :

Springer


Collection :

Springer Theses

Paru le : 2013-08-13



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Description
Ana Escribano Cuesta's thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work involved streamlining the variables that allow the selective synthesis of different products such as tricyclic compounds, dihydropyrans, 1,3-dienes or cyclobutenes. The second chapter highlights the importance and difficulties in synthesising a cyclobutene subunit and the author includes a detailed description of how the products were prepared. The final chapter outlines the synthesis of lundurines using methodology developed by the author's research group for intramolecular gold-catalyzed cyclization of indoles with alkynes. The lundurine products developed in this work show significant in vitro cytoxicity toward B16 melanoma cells. The work in this thesis has led to a number of publications in high-profile chemistry journals.
Pages
195 pages
Collection
Springer Theses
Parution
2013-08-13
Marque
Springer
EAN papier
9783319007014
EAN EPUB
9783319007021
Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
19
Taille du fichier
2386 Ko
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Prix
94,94 €

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