Uri Galili is an immunologist who received his PhD in 1977 at the Hebrew University School of Medicine, Jerusalem, Israel. Following postdoctoral research at the Karolinska Institute, Stockholm (1977-1979), he worked at Hadassah University Hospital, Jerusalem (1979-1984), where he discovered anti-Gal as the most abundant natural antibody in humans. In collaboration with Bruce Macher at University of California Medical Center, San Francisco (1984-1990), he identified the a-gal epitope as the mammalian antigen that binds anti-Gal, determined the unique evolution of anti-Gal and a-gal epitopes in primates and studied the molecular basis for this evolution. In MCP-Hahnemann School of Medicine, Philadelphia (1991-1999), he studied the significance of anti-Gal/a-gal epitope interaction as an immune barrier in xenotransplantation and initiated studies on harnessing anti-Gal in cancer immunotherapy and in amplifying immune response to viruses. At Rush Medical School, Chicago (1999-2004), he studied immune tolerance induction to a-gal epitopes. In the Department of Surgery at UMass Medical School, Worcester (2004-2013), he developed a method for in situ conversion of tumors into autologous vaccines targeted to antigen-presenting cells by intratumoral injection of a-gal glycolipids, performed clinical trials with this immunotherapy and demonstrated increased immunogenicity of influenza and HIV vaccines presenting a-gal epitopes. He further developed anti-Gal binding a-gal nanoparticles that accelerate wound and burn healing and induce tissue regeneration in internal injuries. Prof. Galili retired in 2013 and lives in Chicago. He continues his research as a volunteer Adjunct Professor at Rush Medical School, on a-gal nanoparticles induced regeneration of ischemic myocardium, post myocardial infarction.