Mitochondrial Function in Lung Health and Disease



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Éditeur :

Humana


Collection :

Respiratory Medicine

Paru le : 2014-07-26



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Description
Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.
Pages
222 pages
Collection
Respiratory Medicine
Parution
2014-07-26
Marque
Humana
EAN papier
9781493908288
EAN EPUB
9781493908295

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
22
Taille du fichier
1731 Ko
Prix
73,84 €