Stereoselective Heterocycle Synthesis via Alkene Difunctionalization

Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation

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Éditeur :

Springer


Collection :

Springer Theses

Paru le : 2018-04-02



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Description
This book investigates the use of palladium modified by bulky ligands as catalysts for new chemical transformations that rapidly assemble several classes of complex heterocyles. It documents the development of new chemical reactions involving carbon–carbon (C?C) and carbon–halogen (C?X) bond formation in the context of alkene difunctionalization and dearomatization reactions. Due to the ubiquity of heterocycles in bioactive natural products and life-improving pharmaceutical treatments, a long-term goal for synthetic organic chemists has been to develop novel and creative heterocycle syntheses that illicit a high degree of product diversity and are characterized by mild reaction conditions and limited waste production. A considerable fraction of leading pharmaceutical drugs contain at least one heterocycle within their chemical structure, and their prevalence in these technologies is strong evidence that the fundamental curiosities of organic chemistry lead to real-world solutions for the health and wellness of the global population.

Pages
365 pages
Collection
Springer Theses
Parution
2018-04-02
Marque
Springer
EAN papier
9783319775067
EAN PDF
9783319775074

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
36
Taille du fichier
36475 Ko
Prix
126,59 €
EAN EPUB
9783319775074

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
36
Taille du fichier
4925 Ko
Prix
126,59 €