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Description
Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington's Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins – substrate specificity and inhibitor design, and chemical probes in sirtuin research. This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research. - Presents an excellent subject, excellent structural organization, and authoritative contributions from world-renowned scholars in the sirtuin field - Provides the latest updates on sirtuins in health and disease
Pages
186 pages
Collection
n.c
Parution
2018-02-03
Marque
Academic Press
EAN papier
9780128122617
EAN PDF
9780128122624
Informations sur l'ebook
Nombre pages copiables
18
Nombre pages imprimables
18
Taille du fichier
9349 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
128,71 €
EAN EPUB SANS DRM
9780128122624
Informations sur l'ebook
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
128,71 €

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