DJ-1/PARK7 Protein

Parkinson's Disease, Cancer and Oxidative Stress-Induced Diseases

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Springer


Paru le : 2017-11-16



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Description
This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The DJ-1 gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a causative gene for a familial form of Parkinson’s disease (PD), park7. The DJ-1 gene is therefore the first gene discovered that is known to cause cancer and neurodenegerative diseases, including PD. The research field has expanded as the research has developed. Thus this volume begins with a general introduction of DJ-1, and explains the history and research development to understand the following chapters. Those chapters present the roles of DJ-1 in various oxidative stress-related diseases such as neurodegenerative diseases, as well as cancer, diabetes, and fertility. Moreover, several chapters present evidence that DJ-1 is useful for therapeutic strategies against these diseases. The reader willdiscover that DJ-1 is a promising protein both for basic cell biology and for the mechanism and therapy for oxidative stress-related diseases. 























Pages
222 pages
Collection
n.c
Parution
2017-11-16
Marque
Springer
EAN papier
9789811065828
EAN PDF
9789811065835

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
22
Taille du fichier
10301 Ko
Prix
147,69 €
EAN EPUB
9789811065835

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
22
Taille du fichier
3369 Ko
Prix
147,69 €

Hiroyoshi Ariga
Faculty of Pharmaceutical Sciences, Hokkaido University
Sapporo, Japan

Sanae M.M. Iguchi-Ariga
Faculty of Agriculture, Hokkaido University
Sapporo,Japan

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