Dual-Mode Electro-photonic Silicon Biosensors

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Éditeur :

Springer


Collection :

Springer Theses

Paru le : 2017-07-18

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Description
This highly interdisciplinary thesis reports on two innovative photonic biosensors that combine multiple simultaneous measurements to provide unique insights into the activity and structure of surface immobilized biological molecules. In addition, it presents a new silicon photonic biosensor that exploits two cascaded resonant sensors to provide two independent measurements of a biological layer immobilized on the surface. By combining these two measurements, it is possible to unambiguously quantify the density and thickness of the molecular layer; here, the approach’s ability to study molecular conformation and conformational changes in real time is demonstrated.


The electrophotonic biosensor integrates silicon photonics with electrochemistry into a single technology. This multi-modal biosensor provides a number of unique capabilities that extend the functionality of conventional silicon photonics. For example, by combining the complementary information revealed bysimultaneous electrochemical and photonic measurements, it is possible to provide unique insights into on-surface electrochemical processes. Furthermore, the ability to create electrochemical reactions directly on the silicon surface provides a novel approach for engineering the chemical functionality of the photonic sensors. The electrophotonic biosensor thus represents a critical advance towards the development of very high-density photonic sensor arrays for multiplexed diagnostics.

Pages
149 pages
Collection
Springer Theses
Parution
2017-07-18
Marque
Springer
EAN papier
9783319605005
EAN PDF
9783319605012

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
14
Taille du fichier
7055 Ko
Prix
94,94 €
EAN EPUB
9783319605012

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
14
Taille du fichier
3308 Ko
Prix
94,94 €