Téléchargez le livre : Oral Bioavailability Assessment

Oral Bioavailability Assessment

Basics and Strategies for Drug Discovery and Development de

Éditeur :

Wiley


Collection :

Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods

Paru le : 2017-05-15

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Description
Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.

•    Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability
•    Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development
•    Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development
•    Includes chapters about pharmacokinetic  modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)
•    Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development
Pages
448 pages
Collection
Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods
Parution
2017-05-15
Marque
Wiley
EAN papier
9781118916698
EAN PDF
9781118916940
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
448
Taille du fichier
9564 Ko
Prix
183,52 €
EAN EPUB
9781118916933
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
448
Taille du fichier
12739 Ko
Prix
183,52 €

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