Téléchargez le livre :  BACE

BACE

Lead Target for Orchestrated Therapy of Alzheimer's Disease

de

Éditeur :

Wiley


Paru le : 2010-03-05



eBook Téléchargement DRM Adobe 🛈
131,82

Téléchargement immédiat
Dès validation de votre commande
Ajouter à ma liste d'envies
Image Louise Reader présentation

Louise Reader

Lisez ce titre sur l'application Louise Reader.

Description

BACE inhibitors and their use in the treatment of Alzheimer's Disease
BACE (ß-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery.
This book details the story of the discovery of BACE and its role in AD and comprehensively discusses: The development of BACE inhibitors as therapeutics for Alzheimer's disease The research that led to the identification of BACE New BACE inhibitors currently being clinically tested ADME (absorption, distribution, metabolism, excretion) and clinical trial design—topics not addressed in current field literature Cutting-edge technology such as high-throughput screening, structure-based drug design, and QSAR in context of BACE inhibitors and Alzheimer's drug discovery Other approaches to BACE inhibition based on interaction with the precursor protein APP
By enhancing the reader's understanding of the various aspects of the BACE drug-discovery process, this much-needed reference will serve as a key resource for all scientists involved in Alzheimer's research—and inspire new approaches to treatment of AD.
Pages
272 pages
Collection
n.c
Parution
2010-03-05
Marque
Wiley
EAN papier
9780470293423
EAN PDF
9780470594070

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
272
Taille du fichier
11172 Ko
Prix
131,82 €

Suggestions personnalisées