Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)



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Springer


Paru le : 2015-07-28



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Description
Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to its metabolic and skeletal functions, TNAP also plays a role in regulating cerebral functions, most probably cognition. In fact, TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer's disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs.
Pages
395 pages
Collection
n.c
Parution
2015-07-28
Marque
Springer
EAN papier
9789401771962
EAN PDF
9789401771979

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
39
Taille du fichier
9196 Ko
Prix
210,99 €
EAN EPUB
9789401771979

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
39
Taille du fichier
4393 Ko
Prix
210,99 €

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