Sigma Receptors: Their Role in Disease and as Therapeutic Targets



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Springer


Paru le : 2017-03-16



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Description

Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types.  It’s putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors.  Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein.
Pages
312 pages
Collection
n.c
Parution
2017-03-16
Marque
Springer
EAN papier
9783319501727
EAN PDF
9783319501741

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
12954 Ko
Prix
168,79 €
EAN EPUB
9783319501741

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
4844 Ko
Prix
168,79 €

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