Bone Morphogenetic Proteins: Systems Biology Regulators



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Éditeur :

Springer


Collection :

Progress in Inflammation Research

Paru le : 2017-03-14



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Description

This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes.
This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.


Pages
445 pages
Collection
Progress in Inflammation Research
Parution
2017-03-14
Marque
Springer
EAN papier
9783319475059
EAN PDF
9783319475073

Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
44
Taille du fichier
10844 Ko
Prix
210,99 €
EAN EPUB
9783319475073

Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
44
Taille du fichier
3656 Ko
Prix
210,99 €