Téléchargez le livre : G Protein-Coupled Receptors as Drug Targets

G Protein-Coupled Receptors as Drug Targets

Analysis of Activation and Constitutive Activity de

,

Éditeur :

Wiley-VCH


Collection :

Methods & Principles in Medicinal Chemistry

Paru le : 2006-05-12

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Description
With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on GPCRs. The international team of highly distinguished authors addresses in detail current models and concepts, to introduce medicinal chemists, physiologists, pharmacologists, and medical researchers into the advances in the understanding of GPCR activation and constitutive activity. In addition, the book provides an overview on methods of investigating constitutive GPCR activity. The text is well illustrated by selected experimental data and schemes._The chaptes are all cross-referenced with each other and cover general mechnisms, methodological approaches and cover selected important GPCR sysstems, the consequences for drug action, including, side effects, and rational drug design for GPCR targets. A highly recommended reference for researchers in academia and industry.

authors addresses in detail current models and concepts, so as to introduce pharmaceutical chemists, physiologists and medical researchers to the advances in the understanding of GPCR activation and constitutive activity, and provides an overview of the methods of investigating GPCR activity. The text is backed by abundant case studies and methodological advice for analyzing GPCRs, covering selected pharmacologically relevant GPCR systems, the consequences for drug action, including unwanted side effects, and rational drug design for GPCR targets.
A highly practical reference for researchers in academia and industry.
Pages
304 pages
Collection
Methods & Principles in Medicinal Chemistry
Parution
2006-05-12
Marque
Wiley-VCH
EAN papier
9783527308194
EAN PDF
9783527606955
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
304
Taille du fichier
2683 Ko
Prix
232,05 €

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