Metal-Based Neurodegeneration

From Molecular Mechanisms to Therapeutic Strategies de

,

Éditeur :

Wiley


Paru le : 2013-09-04

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Description

Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies.
Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scientific findings,  including details of their biochemical actors (proteins or peptides), their normal and pathological conformations, and a description of the diseases characteristics, with an emphasis on the role of metal-induced oxidative stress, which can result in the production of intracellular aggregates of target proteins and peptides. 
Topics covered include: Brain function, physiology and the blood-brain barrier Immune system and neuroinflammation Aging and mild cognitive impairment, MCI Parkinson’s Disease Alzheimer’s Disease Creutzfelt-Jakob and related prion diseases Alcoholic Brain Damage Therapeutic strategies to combat the onset and progression of neurological diseases
This extensively updated, full colour, second edition of Metal-based Neurodegeneration is an essential text for research scientists and clinicians working in gerontology, neuropathology, neurochemistry, and metalloprotein mechanisms.
Pages
440 pages
Collection
n.c
Parution
2013-09-04
Marque
Wiley
EAN papier
9781119977148
EAN PDF
9781118553497

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
440
Taille du fichier
45947 Ko
Prix
173,79 €
EAN EPUB
9781118553510

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
440
Taille du fichier
14756 Ko
Prix
173,79 €

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