Téléchargez le livre : Chromosomal Instability in Cancer Cells

Chromosomal Instability in Cancer Cells

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Éditeur :

Springer


Collection :

Recent Results in Cancer Research

Paru le : 2015-09-16

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Description

This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.
Pages
224 pages
Collection
Recent Results in Cancer Research
Parution
2015-09-16
Marque
Springer
EAN papier
9783319202907
EAN PDF
9783319202914
Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
22
Taille du fichier
5765 Ko
Prix
52,74 €
EAN EPUB
9783319202914
Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
22
Taille du fichier
2335 Ko
Prix
52,74 €

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