Téléchargez le livre : Concepts and Models for Drug Permeability Studies

Concepts and Models for Drug Permeability Studies

Cell and Tissue based In Vitro Culture Models de

Éditeur :

Woodhead Publishing


Paru le : 2015-09-30

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Description
This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. - Updated information regarding the most recent in vitro models to study the permeability of drugs - Short and concise chapters covering all the biological barriers with interest in drug permeability - A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models - Simple and clear scientific content, adaptable for young scientists and experimented researchers
Pages
408 pages
Collection
n.c
Parution
2015-09-30
Marque
Woodhead Publishing
EAN papier
9780081000946
EAN PDF
9780081001141
Informations sur l'ebook
Nombre pages copiables
40
Nombre pages imprimables
40
Taille du fichier
11837 Ko
Prix
156,14 €
EAN EPUB SANS DRM
9780081001141
Informations sur l'ebook
Prix
156,14 €

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