Téléchargez le livre : Annotating New Genes

Annotating New Genes

From in Silico Screening to Experimental Validation

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Éditeur :

Woodhead Publishing


Paru le : 2012-08-06



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Description
In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. - Focuses not only on screening but also on biological validations - Provides details of databases and software (web interface) products for biologists with minimal computation skills - Offers a step-by-step outline of the procedure involved
Pages
196 pages
Collection
n.c
Parution
2012-08-06
Marque
Woodhead Publishing
EAN papier
9781907568688
EAN EPUB SANS DRM
9781908818126
Informations sur l'ebook
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Prix
144,53 €
Shizuka Uchida is a group leader in the Max-Planck Institute for Heart and Lung Research in Bad Nauheim, Germany. He is a trained bioinformatician and a developmental biologist with a specific focus on adult stem cell research, and has extensive experience in combining the power of computers and data mining methods with state-of-the-art experimental techniques.

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