Téléchargez le livre : Transgenerational Epigenetics
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Description
Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations. This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research. - Focused discussion of metabolic disorders, cardiovascular diseases and longevity, which appear most affected by reversible and heritable epigenetic processes - Encompasses both foundational and clinical aspects including discussions of preventative in utero therapies - Covers history, future outlook, disease management and current controversies
Pages
412 pages
Collection
n.c
Parution
2014-05-02
Marque
Academic Press
EAN papier
9780124059443
EAN PDF
9780124059221
Informations sur l'ebook
Nombre pages copiables
41
Nombre pages imprimables
41
Taille du fichier
16210 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
124,49 €

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