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Reagents for Silicon-Mediated Organic Synthesis



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Éditeur :

Wiley


Collection :

Handbook of Reagents for Organic Synthesis

Paru le : 2013-05-30



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Description
Over the last three decades the importance of organosilicon chemistry has greatly increased because it has opened a number of new synthetic strategies. Silicon reagents are usually low-cost, versatile and allow a wide range of reactions. This is the first Handbook to compile essential Silicon containing reagents and makes use of the leading reagent database e-EROS. Another hot volume in the series Handbooks of Reagents for Organic Synthesis, this is a must-have resource for all synthetic chemists working in drug development and medicinal chemistry.
For the selection the Editor focussed on three key synthetic approaches with the greatest impact:
1. Use of silicon as a 'temporary tether' by unifying a reactive pair of functional groups and taking advantage of their template-biased intramolecular cyclization.
2. The specific use of the silane functionality as a hetero t-butyl group, often colloquially referred to as the use of silicon as a 'fat proton'.
3. The use of the Brook rearrangement as an 'anion relay stratagem'.
A new feature in this Handbook is the reagent finder, an alphabetically organized lookup table arranged by organic functionality and specific structure of the silicon atom to which it is bound.
Pages
816 pages
Collection
Handbook of Reagents for Organic Synthesis
Parution
2013-05-30
Marque
Wiley
EAN papier
9780470710234
EAN PDF
9781118636138

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
816
Taille du fichier
21012 Ko
Prix
138,15 €