Téléchargez le livre : Diversity-Oriented Synthesis

Diversity-Oriented Synthesis

Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

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Éditeur :

Wiley


Paru le : 2013-06-17



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Description

Discover an enhanced synthetic approach to developing and screening chemical compound libraries
Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.
Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research
This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.
Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.
Pages
664 pages
Collection
n.c
Parution
2013-06-17
Marque
Wiley
EAN papier
9781118145654
EAN PDF
9781118617946
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
664
Taille du fichier
57508 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
165,58 €
EAN EPUB
9781118618141
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
664
Taille du fichier
15647 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
165,58 €

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