Téléchargez le livre : Molecular Pharmacology

Molecular Pharmacology

From DNA to Drug Discovery

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Éditeur :

Wiley


Paru le : 2012-11-30



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Description

This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments.
Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.
Pages
432 pages
Collection
n.c
Parution
2012-11-30
Marque
Wiley
EAN papier
9780470684443
EAN PDF
9781118451977
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
432
Taille du fichier
10332 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
164,50 €
EAN EPUB
9781118451953
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
432
Taille du fichier
27873 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
82,22 €

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