Ubiquitin Proteasome System in CNS Neurodegenerative Diseases



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Springer


Paru le : 2026-02-23



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Description

This book provides up-to-date information on the mechanisms of protein degradation and highlights the significance of protein quality control for cellular physiology and pathology specifically in CNS neurodegenerative diseases. Chapters cover cellular bioenergetics, environmental factors, protein load, and their respective roles in the pathogenesis and progression of diseases. Additionally, the book addresses the array of experimental tools (models) available for studying disease etiology, progression, and therapeutics, offering a balanced discussion of their advantages and disadvantages. It provides insights into the effects of both sporadic and genetic models in investigating disease mechanisms, with a perspective on experimental model systems.
The book is relevant for scientists and researchers in the fields of neuroscience, cellular signaling, protein, and systems biology. It is also valuable for clinicians interested in both basic and translational research in the field of central nervous system (CNS) neurodegenerative diseases.
Pages
378 pages
Collection
n.c
Parution
2026-02-23
Marque
Springer
EAN papier
9789819560981
EAN PDF
9789819560998

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
37
Taille du fichier
8571 Ko
Prix
210,99 €
EAN EPUB
9789819560998

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
37
Taille du fichier
12022 Ko
Prix
210,99 €

Dr. Sarika Singh completed her master's in biochemistry and a Ph.D. in the role of nitric oxide in the pathology of Parkinson’s disease from Lucknow University, Lucknow, India. She is working as a senior principal scientist and Professor at the Academy of Scientific and Innovative Research (AcSIR) at CSIR-Central Drug Research Institute in Lucknow, Uttar Pradesh, India. Dr. Singh’s major research focuses on identifying diagnostic markers and novel signaling factors participate in neurodegeneration. She is actively involved in search for novel therapeutic molecule for management of Alzheimer’s and Parkinson’s diseases. Her exploratory studies target the contributions of bioenergetics and unfolded protein responses in neurodegenerative conditions. She has published over 85 articles in peer-reviewed national and international journals and is an editorial board member and reviewer for various journals. Dr. Singh is a lifetime member of the Indian Academy of Neurosciences and the National Academy of Sciences.

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