Massimo Filippi is Professor of Neurology at Università Vita-Salute San Raffaele, Milan, Italy. Prof. Filippi is currently Director of the BrainMap Project and Director of the Neuroimaging Research Unit (NRU), Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Milan, Italy. His research activity has always been focused on the use of MR-based technology to improve our understanding of how neurological diseases determine progressive accumulation of irreversible physical disability and cognitive impairment. As Director of the NRU, he coordinated the MRI acquisition and analysis of several large-scale international MRI-monitored trials of MS.