Katherine Clarke undertook her BA in Classics (Literae Humaniores) at St John's College, Oxford, before going on to obtain her D.Phil. in Ancient History also at Oxford in 1996, where she held a Graduate Scholarship followed by a Junior Research Fellowship, both at Christ Church. In 1998 she was appointed to the Tutorial Fellowship in Ancient History at St Hilda's College, where she has remained ever since. She was the recipient of a Philip Leverhulme Prize for the period 2001-3 and has held various positions of responsibility in both her College and the university's Faculty of Classics including Vice Principal in College, 2013-16, and Chair of the Sub-Faculty, 2015-17.