An Integrated Guide to Human Drug Metabolism

From Basic Chemical Transformations to Drug-Drug Interactions de

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Academic Press


Paru le : 2024-05-13

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An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines and other drugs. Each of the human metabolic processes will be covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, An Integrated Guide to Human Drug Metabolism is useful for students and researchers needing a reference for interdisciplinary research in drug interactions.
Metabolism is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects.Covers each of the human metabolic processes, employing examples drawn from known metabolic transformations of drugs used clinicallyProvides an integrated approach, linking together the science and practice strands of human drug metabolismContains questions and answers to assess learning of material and real-life case studies

Elsevier Science & Technology
Pages
250 pages
Collection
n.c
Parution
2024-05-13
Marque
Academic Press
EAN papier
9780323991339
EAN PDF
9780323993753

Informations sur l'ebook
Nombre pages copiables
25
Nombre pages imprimables
25
Taille du fichier
25446 Ko
Prix
137,15 €
EAN EPUB SANS DRM
9780323993753

Informations sur l'ebook
Prix
137,15 €

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