Téléchargez le livre : Neurotoxicity of Aluminum

Neurotoxicity of Aluminum



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Éditeur :

Springer


Paru le : 2023-07-08



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Description

This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment.

The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. 
In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
Pages
313 pages
Collection
n.c
Parution
2023-07-08
Marque
Springer
EAN papier
9789819915910
EAN PDF
9789819915927
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
9974 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
189,89 €
EAN EPUB
9789819915927
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
42107 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
189,89 €

Dr. Qiao Niu is a professor and director of the Department of Occupational Health, School of Public Health, Shanxi Medical University. He is also director of the Institute of Preventive Medicine at the same university. Dr. Niu is executive director of the Chinese Society for Toxicology, and of the Labor Health and Occupational Disease Branch of the Chinese Preventive Medicine Association. His research focuses on neurotoxicology, an area in which he has published more than 200 research articles.

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