Téléchargez le livre : Inducing Targeted Protein Degradation

Inducing Targeted Protein Degradation

From Chemical Biology to Drug Discovery and Clinical Applications

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Éditeur :

Wiley-VCH


Paru le : 2022-11-15



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Description
Inducing Targeted Protein Degradation
Enables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation
Since the breakthrough of the PROTAC technology in 2015, targeted protein degradation has revolutionized drug discovery, enabling pharma companies to develop completely novel therapeutics. Inducing Targeted Protein Degradation is a timely guide to navigating the complexities of the subject and understanding its practical application, with an eye on expanding the druggable space.
In Inducing Targeted Protein Degradation, readers will find the most recent information on: Cellular mechanisms of targeted protein degradation and current approaches to utilize these mechanisms for drug discovery A comparison of different induced degradation approaches, including PROTAC, molecular glues, LYTACs and ATTECs as well as additional post translational modifications Drug development aspects such as DMPK optimization and criteria for the selection of clinical candidates A discussion of the potential of targeted degradation for expanding the druggable space

Inducing Targeted Protein Degradation will serve as a practice-oriented reference on induced protein degradation for drug discovery professionals and for researchers employing chemical biology approaches.
Pages
384 pages
Collection
n.c
Parution
2022-11-15
Marque
Wiley-VCH
EAN papier
9783527350131
EAN PDF
9783527350179
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
384
Taille du fichier
52214 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
149,07 €
EAN EPUB
9783527836215
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
384
Taille du fichier
32696 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
149,07 €

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