The Chemical Biology of Long Noncoding RNAs

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Éditeur :

Springer


Collection :

RNA Technologies

Paru le : 2020-10-01

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Description

This book offers a comprehensive and detailed overview of various aspects of long non-coding RNAs. It discusses their emerging significance in molecular medicine, ranging from human cancers to cardiovascular and metabolic diseases.
Transcriptomic studies have demonstrated that the majority of genomes found in complex organisms are expressed in highly dynamic and cell-specific patterns, producing huge numbers of intergenic, antisense and intronic long non-protein-coding RNAs (lncRNAs). Thousands of lncRNAs have been identified, and unlike mRNA, they have no protein-coding capacity. A large repertoire of ncRNAs, actively transcribed from the mammalian genome, control diverse cellular processes, both in terms of development and diseases, through a variety of gene regulatory mechanisms. IncRNAs have emerged as a new paradigm in epigenetic regulation of the genome.

Given its scope, the book will be of particular interest to molecular, chemical, cell and developmental biologists, as well as specialists in translational medicine involved in disease-oriented research. It also offers a valuable resource for in silico experts seeking a deeper understanding of lncRNA expression and function through computational analysis of the NGS data. 
Pages
545 pages
Collection
RNA Technologies
Parution
2020-10-01
Marque
Springer
EAN papier
9783030447427
EAN PDF
9783030447434

Informations sur l'ebook
Nombre pages copiables
5
Nombre pages imprimables
54
Taille du fichier
11387 Ko
Prix
147,69 €
EAN EPUB
9783030447434

Informations sur l'ebook
Nombre pages copiables
5
Nombre pages imprimables
54
Taille du fichier
28764 Ko
Prix
147,69 €