Téléchargez le livre : The Human Mitochondrial Genome

The Human Mitochondrial Genome

From Basic Biology to Disease

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Éditeur :

Academic Press


Paru le : 2020-07-23



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Description
The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including cancer, neurodegenerative, age-related, mtDNA depletion, deletion, and point mutation diseases. Nucleosides supplementation, mitoTALENs, and mitoZNF nucleases are among the therapeutic approaches examined in-depth. With increasing funding for mtDNA studies, many clinicians and clinician scientists are turning their attention to mtDNA disease association. This book provides the tools and background knowledge required to perform new, impactful research in this exciting space, from distinguishing a haplogroup-defining variant or disease-related mutation to exploring emerging therapeutic pathways. - Fully examines recent advances and technological innovations in the field, enabling new mtDNA studies, variant and mutation identification, pathogenic assessment, and therapies - Disease discussion accompanied by diagnostic and therapeutic strategies currently implemented clinically - Outlines and discusses essential research protocols and perspectives for young scientists to pick up - Features an international team of authoritative contributors from basic biologists to clinician-scientists
Pages
596 pages
Collection
n.c
Parution
2020-07-23
Marque
Academic Press
EAN papier
9780128196564
EAN PDF
9780128226421
Informations sur l'ebook
Nombre pages copiables
59
Nombre pages imprimables
59
Taille du fichier
9492 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
174,07 €
EAN EPUB SANS DRM
9780128226421
Informations sur l'ebook
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
174,07 €

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