Téléchargez le livre : Mass Spectrometry-Based Chemical Proteomics

Mass Spectrometry-Based Chemical Proteomics



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Wiley


Paru le : 2019-07-31



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Description

PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT
Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments.
The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry
Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.
Pages
448 pages
Collection
n.c
Parution
2019-07-31
Marque
Wiley
EAN papier
9781118969557
EAN PDF
9781118970218
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
448
Taille du fichier
7526 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
199,59 €
EAN EPUB
9781118970201
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
448
Taille du fichier
50801 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
199,59 €

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