Téléchargez le livre : Thymus Transcriptome and Cell Biology

Thymus Transcriptome and Cell Biology

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Éditeur :

Springer


Paru le : 2019-04-11

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Description

This volume focuses on challenging field in biomedicine that is the genetic control of central immune tolerance. It covers the thymus development, their cellular components and their respective function, the peculiar gene expression profiling (transcriptome) found in the medullary thymic epithelial cells (mTECs) that are implicated in the self-representation in the thymus, the Autoimmune regulator (Aire) gene, the mutations in this gene and manifestation of autoimmune diseases, and the role of cell-cell interactions within the thymus with implications in the negative selection (elimination) of nascent autoreactive T cells in preventing aggressive autoimmunity.

The thymus gland is a lymphoid organ implicated in the maturation, differentiation and selection of T cells. This organ is gained more and more attention in different biomedical research labs worldwide due to its function that is associated with the control of immune homeostasis in the body, establishing the central immune tolerance and preventing the onset of autoimmune diseases.
Pages
318 pages
Collection
n.c
Parution
2019-04-11
Marque
Springer
EAN papier
9783030120399
EAN PDF
9783030120405
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
7936 Ko
Prix
147,69 €
EAN EPUB
9783030120405
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
31
Taille du fichier
16271 Ko
Prix
147,69 €

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