Téléchargez le livre : Phosphodiesterases as Drug Targets

Phosphodiesterases as Drug Targets

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Éditeur :

Springer


Collection :

Handbook of Experimental Pharmacology

Paru le : 2011-06-21

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Description
Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.
Pages
522 pages
Collection
Handbook of Experimental Pharmacology
Parution
2011-06-21
Marque
Springer
EAN papier
9783642179686
EAN EPUB
9783642179693
Informations sur l'ebook
Nombre pages copiables
5
Nombre pages imprimables
52
Taille du fichier
3000 Ko
Prix
304,89 €

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