Thymic Development and Selection of T Lymphocytes

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Springer


Collection :

Current Topics in Microbiology and Immunology

Paru le : 2013-11-06

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Description

The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
Pages
132 pages
Collection
Current Topics in Microbiology and Immunology
Parution
2013-11-06
Marque
Springer
EAN papier
9783642402517
EAN EPUB
9783642402524

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
13
Taille du fichier
799 Ko
Prix
94,94 €