Pharmacotherapy of Pulmonary Hypertension

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Éditeur :

Springer


Collection :

Handbook of Experimental Pharmacology

Paru le : 2013-10-04

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Description

This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.
Pages
576 pages
Collection
Handbook of Experimental Pharmacology
Parution
2013-10-04
Marque
Springer
EAN papier
9783642386633
EAN PDF
9783642386640

Informations sur l'ebook
Nombre pages copiables
5
Nombre pages imprimables
57
Taille du fichier
9073 Ko
Prix
357,64 €
EAN EPUB
9783642386640

Informations sur l'ebook
Nombre pages copiables
5
Nombre pages imprimables
57
Taille du fichier
4567 Ko
Prix
357,64 €