Téléchargez le livre : Pediatric Cancer, Volume 2

Pediatric Cancer, Volume 2

Teratoid/Rhabdoid, Brain Tumors, and Glioma

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Éditeur :

Springer


Paru le : 2012-03-20



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Description
A general introduction to the principles of diagnosis and treatment of children with brain tumors is presented. Molecular characterization of solid tumors is also presented. Molecular pathways provide putative targets for new therapies. High resolution magic spinning NMR spectroscopy is explained, which is used to determine metabolic profiles for small pieces of intact tissue and whole cells in culture. The differences between adult and pediatric brain tumors are outlined. It is emphasized that pediatric low-grade gliomas need lower doses of antidrugs such as cisplatin/etoposide. It is explained that tumor suppressor genes and oncogenes play a crucial role in the development and progression of human malignancies, including those in children. Neurofibromatosis type-1 is a common genetic disorder with a high prevalence in CNS abnormalities including tumors in children; which is discussed in detail. Various neuroradiological imaging modalities in children with leukemia are detailed. Also are detailed results of clinical trials in pediatric brain tumors, such as medulloblastoma, ependymoma, craniopharyngioma, low-grade glioma, high-grade glioma, brainstem glioma, and germ cell tumors, using radiotherapy. Considering the clinical importance of epilepsy in the primary brain tumors in children, its symptoms, diagnosis, and treatments (surgery and antiepileptic drugs) are discussed.
Pages
352 pages
Collection
n.c
Parution
2012-03-20
Marque
Springer
EAN papier
9789400729568
EAN EPUB
9789400729575
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
35
Taille du fichier
3041 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
213,99 €

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