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Description

This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed.
The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection.
Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.
Pages
292 pages
Collection
Advances in Experimental Medicine and Biology
Parution
2013-03-12
Marque
Springer
EAN papier
9781461461104
EAN EPUB
9781461461111

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
29
Taille du fichier
1505 Ko
Prix
147,69 €